Medication 7-260 - Haldol (Haloperidol)
Polk, Hickory, Cedar, & St Clair EMS Protocols
Scope of Practice:
- Registered Nurse
- Paramedic
Route(s):
Pharmacodynamics (class and mechanism of action):
- Antipsychotic (Competitive postsynaptic dopamine receptor blocker).
Pharmacokinetics:
- Half-life: 21 hours.
- Onset time: Unknown.
- Peak action time:
- IM: 10-20 minutes.
- IO/IV: Unknown.
- Duration of action: Unknown.
Peak | 126 | 252 | 378 | 504 | 630 | 756 | 882 | 1008 | 1134 | 1260 | 1386 | minutes |
Duration | 126 | 252 | 378 | 504 | 630 | 756 | 882 | 1008 | 1134 | 1260 | 1386 | minutes |
Dosing:
- Refer to specific protocol(s) below for dose(s).
Indications:
Contraindications:
- Parkinson’s disease.
- Severe CNS depression.
- Comatose states.
Pregnancy Risk Factor:
- Category C
- Risk not ruled out: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. FDA requires a relatively large amount of high-quality data on a pharmaceutical for it to be defined as Pregnancy Category A. As a result of this, many drugs that would be considered Pregnancy Category A in other countries are allocated to Category C by the FDA.
Potential Incompatibilities:
Precautions and Adverse Effects:
- Use caution with severe cardiovascular disorders due to possible hypotension. If vasopressor is needed, use Levophed.
- May prolong QT interval. 12-lead is indicated after administration.
- May cause drowsiness, tardive dyskinesia, hypotension, Hypertension, Tachycardia, and/or Torsades de Pointes.
- Possible Extra-Pyramidal Symptoms (EPS) / dystonic reactions:
Antidote:
Controlled Substance Information:
- Not a scheduled drug
- The DEA and FDA have not identified this drug with a schedule classification.
- DEA number: NA.
- Narcotic: No.
- Street names: NA.
Change Log:
Date | Link topreviousversion | Description of change |
---|
04/01/15 | pdf | Added comment about prolonging QT interval and the need for 12-lead. |
08/24/18 | pdf | Added antidote option of Benadryl. |
05/10/20 | pdf | Added content (without substantive modification) from old Protocol 7-260 - Haldol. |
06/11/21 | pdf | Moved to emsprotocols.online |
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