Medication 7-400 - Narcan (Naloxone)

Polk, Hickory, Cedar, & St Clair EMS Protocols

Scope of Practice:

• Emergency Medical Responder
• Emergency Medical Technician
• Advanced Emergency Medical Technician
• Registered Nurse
• Paramedic

Route(s):

• ET, IM/SQ, IN, IO, IV,

Pharmacodynamics (class and mechanism of action):

• Narcotic antagonist. (Binds to opiod receptor and blocks the effect of Narcotics.).

Pharmacokinetics:

• Half-life:
• Adults: 80-90 minutes.
• Neonates: 3 hours.
• Onset time:
• IM: 2-5 minutes.
• IV: 1-2 minutes.
• Peak action time: 5-15 minutes.
• Duration of action: Variable.

• Peak	9	18	27	36	45	54	63	72	81	90	minutes
  Duration	9	18	27	36	45	54	63	72	81	90	minutes

Dosing:

• Refer to specific protocol(s) below for dose(s).

Indications:

• Protocol 2-198 - Cardiac Arrest.
• Protocol 2-616 - Newly Born.
• Protocol 2-638 - Overdose / Toxic Ingestion.
• Medication 7-230 - Fentanyl.
• Medication 7-390 - Morphine.

Contraindications:

• Hypersensitivity.

Pregnancy Risk Factor:

• Category B
• No risk in other studies: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women, or animal studies have shown adverse effects, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Potential Incompatibilities:

• None.

Precautions and Adverse Effects:

• Short acting, should be augmented every 5 minutes.
• Monitor airway and ventilatory status.
• Patients who have gone from a state of somnolence from a Narcotic Overdose may become wide awake and Combative.
• May cause withdrawal effects, Nausea, Vomiting, restlessness, diaphoresis, Tachycardia, Hypertension, tremulousness, Seizure, and/or Cardiac Arrest.

Antidote:

• None.

Controlled Substance Information:

• Not a scheduled drug
• The DEA and FDA have not identified this drug with a schedule classification.
• DEA number: NA.
• Narcotic: No.
• Street names: NA.

CMH PHS Mission: "Provide safe, exceptional, and compassionate care to our communities with an emphasis on highly trained and empowered staff."

Polk, Hickory, Cedar, & St Clair County EMS Protocols by Theron Becker is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.