Medication 7-888 - Thiamine (Vitamin B1)

CMH EMS & MIH Protocols

Scope of Practice:

• Registered Nurse
• Paramedic
• Community Paramedic

Route(s):

• IM/SQ, IO, IV,

Pharmacodynamics (class and mechanism of action):

• Vitamin. (Allows normal breakdown of Glucose. Thiamine combines with adenosine triphosphate to produce thiamine diphosphate, which acts as a coenzyme in carbohydrate metabolism. Used to prevent Wernicke’s encephalopathy in patients with a history of alcohol dependence and Hypoglycemia.)

Pharmacokinetics:

• Half-life: NA.
• Onset time: NA.
• Peak action time: NA.
• Duration of action: NA.

• Peak	1	minutes
  Duration	1	minutes

Dosing:

• Refer to specific protocol(s) below for dose(s).

Indications:

• Protocol 2-572 - Hypoglycemia.
• Medication 7-252 - Dextrose.

Contraindications:

• Known sensitivity.

Pregnancy Risk Factor:

• Category A
• No risk in controlled human studies: Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).

Potential Incompatibilities:

• None.

Precautions and Adverse Effects:

• May cause rare Anaphylactic Reactions, itching, and/or rash.

Antidote:

• Dantroline.

Controlled Substance Information:

• Not a scheduled drug
• The DEA and FDA have not identified this drug with a schedule classification.
• DEA number: NA.
• Narcotic: No.
• Street names: NA.

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CMH Mobile Integrated Healthcare Mission: "Provide exceptional, compassionate, and patient-centered care by a mobile collaborative team to improve patient experience, improve quality outcomes, and reduce healthcare costs."

Polk, Hickory, Cedar, & St Clair County EMS Protocols is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.