Medication 7-066 - Amiodarone (Cordarone)

CMH EMS & MIH Protocols

Scope of Practice:

• Registered Nurse
• Paramedic
• Community Paramedic

Route(s):

• IO, IV,

Pharmacodynamics (class and mechanism of action):

• Class III antiarrhythmic.
• Potassium channel blocker. Prolongs intranodal conduction. Prolongs refractoriness of the AV node.

Pharmacokinetics:

• Half-life: 40-50 days.
• Onset time: Unknown.
• Peak action time: Unknown.
• Duration of action: Variable.

• Peak	1	minutes
  Duration	1	minutes

Dosing:

• Refer to specific protocol(s) below for dose(s).

Indications:

• Protocol 2-198 - Cardiac Arrest.
• Protocol 2-858 - Supraventricular Tachycardia.
• Protocol 2-946 - Ventricular Tachycardia.
• Protocol 2-968 - V-Fib / Pulseless V-Tach.

Contraindications:

• Pregnancy.
• Cardiogenic shock.
• Sinus Bradycardia.
• 2nd or 3rd degree AV block.
• Sick Sinus Syndrome.
• Sensitivity to benzyl alcohol and iodine.

Pregnancy Risk Factor:

• Category D
• Positive evidence of risk: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Potential Incompatibilities:

• NA.

Precautions and Adverse Effects:

• Use caution with Proarrhythmic with concurrent antiarrhythmic meds.
• Consider slower administration on patients with hepatic or renal dysfunction.
• May prolong QT interval. 12-lead is indicated after administration.
• May cause hypotension, Bradycardia (slow down the rate of infusion).

Antidote:

• Medication 7-175 - Calcium Chloride.
• Medication 7-384 - Glucagon.

Controlled Substance Information:

• Not a scheduled drug
• The DEA and FDA have not identified this drug with a schedule classification.
• DEA number: NA.
• Narcotic: No.
• Street names: NA.

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Polk, Hickory, Cedar, & St Clair County EMS Protocols is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.