Medication 7-340 - Epinephrine Racemic (Micronefrin)

CMH EMS & MIH Protocols

Scope of Practice:

• Registered Nurse
• Paramedic
• Community Paramedic

Route(s):

• Neb,

Pharmacodynamics (class and mechanism of action):

• Nonselective alpha and beta agonist (Arteriole constriction. Positive inotrope. Positive chronotrope. Bronchial smooth muscle relaxant. Blocks histamine release. Inhibits insulin secretion. Relaxes GI smooth muscle.).

Pharmacokinetics:

• Half-life: 2 minutes.
• Onset time: Rapid.
• Peak action time: Unknown.
• Duration of action: 3 minutes.

• Peak	18	36	54	72	90	108	126	144	162	180	198	seconds
  Duration	18	36	54	72	90	108	126	144	162	180	198	seconds

Dosing:

• Refer to specific protocol(s) below for dose(s).

Indications:

• Protocol 2-770 - Respiratory Distress.

Contraindications:

• Glaucoma.
• Elderly.
• Cardiac disease.
• Hypertension.
• Thyroid disease.
• Diabetes.
• Sensitivity to sulfites.

Pregnancy Risk Factor:

• Category C
• Risk not ruled out: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. FDA requires a relatively large amount of high-quality data on a pharmaceutical for it to be defined as Pregnancy Category A. As a result of this, many drugs that would be considered Pregnancy Category A in other countries are allocated to Category C by the FDA.

Potential Incompatibilities:

• NA.

Precautions and Adverse Effects:

• Patient must be observed for 2-4 hours after administration.
• May cause palpitations, anxiety, headache, Hypertension, Nausea, Vomiting, arrhythmias, rebound edema, dizziness, tremors, and/or Tachycardia.

Antidote:

• NA.

Controlled Substance Information:

• Not a scheduled drug
• The DEA and FDA have not identified this drug with a schedule classification.
• DEA number: NA.
• Narcotic: No.
• Street names: NA.

CMH Pre-Hospital Services Mission: "Provide safe, exceptional, and compassionate care to our communities with an emphasis on highly trained and empowered staff."

CMH Mobile Integrated Healthcare Mission: "Provide exceptional, compassionate, and patient-centered care by a mobile collaborative team to improve patient experience, improve quality outcomes, and reduce healthcare costs."

Polk, Hickory, Cedar, & St Clair County EMS Protocols is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.