Medication 7-899 - Toradol (Ketorolac)

CMH EMS & MIH Protocols

Scope of Practice:

• Registered Nurse
• Paramedic
• Community Paramedic

Route(s):

• IM/SQ, IO, IV,

Pharmacodynamics (class and mechanism of action):

• Non-Steroidal Anti-Inflamatory (NSAID). (Inhibit prostaglandin synthesis by decreasing the activity of the enzyme, cyclooxygenase, which results in decreased formation of prostaglandin precursors.)

Pharmacokinetics:

• Half-life: 4-6 hours.
• Onset time:
• IM: 10 minutes.
• IV: Immediate.
• Peak action time:
• IM: 30-60 minutes.
• IV: 1-3 minutes.
• Duration of action: 6-8 hours.

• Peak	42	84	126	168	210	252	294	336	378	420	462	minutes
  Duration	42	84	126	168	210	252	294	336	378	420	462	minutes

Dosing:

• Refer to specific protocol(s) below for dose(s).

Indications:

• Protocol 2-660 - Pain Control.

Contraindications:

• Pregnant or nursing women.
• Allergies to Aspirin, Ibuprofen, or NSAIDs.
• Advanced renal impairment.
• Suspected CVA.
• GI bleeds.
• Peptic ulcers.
• Surgical candidates.

Pregnancy Risk Factor:

• Category D
• Positive evidence of risk: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Potential Incompatibilities:

• None.

Precautions and Adverse Effects:

• Toradol inhibits platelet function.
• Hypersensitivity reactions have occurred (Bronchospasm and Anaphylaxis).
• Avoid in patients currently taking anticoagulants such as Coumadin.
• Can cause peptic ulcers, gastrointestinal bleeding and/or perforation.
• May adversely affect fetal circulation and the uterus.

Antidote:

• None.

Controlled Substance Information:

• Not a scheduled drug
• The DEA and FDA have not identified this drug with a schedule classification.
• DEA number: NA.
• Narcotic: No.
• Street names: NA.

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Polk, Hickory, Cedar, & St Clair County EMS Protocols is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.