Medication 7-417 - Heparin

CMH EMS & MIH Protocols

Scope of Practice:

• Registered Nurse
• Paramedic
• Community Paramedic

Route(s):

• IV,

Pharmacodynamics (class and mechanism of action):

• Anticoagulant (Inhibition of Thrombin. Acts on antithrombin III to reduce ability to clot.).

Pharmacokinetics:

• Half-life: 1-2 hours.
• Onset time: Immediate.
• Peak action time: Unknown.
• Duration of action: Variable.

• Peak	9	18	27	36	45	54	63	72	81	90	99	minutes
  Duration	9	18	27	36	45	54	63	72	81	90	99	minutes

Dosing:

• Refer to specific protocol(s) below for dose(s).

Indications:

• Protocol 2-220 - Chest Pain / Suspected Cardiac Event.

Contraindications:

• Previously given low molecular weight Heparin.
• Dissecting thoracic aortic aneurysm.
• Peptic ulceration.

Pregnancy Risk Factor:

• Category C
• Risk not ruled out: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. FDA requires a relatively large amount of high-quality data on a pharmaceutical for it to be defined as Pregnancy Category A. As a result of this, many drugs that would be considered Pregnancy Category A in other countries are allocated to Category C by the FDA.

Potential Incompatibilities:

• Medication 7-121 - Atropine.
• Medication 7-263 - Dilaudid.
• Medication 7-373 - Fentanyl.
• Medication 7-592 - Morphine.
• Medication 7-702 - Phenergan.
• Medication 7-954 - Versed.

Precautions and Adverse Effects:

• Use caution with oral anticoagulants and bleeding.

Antidote:

• NA.

Controlled Substance Information:

• Not a scheduled drug
• The DEA and FDA have not identified this drug with a schedule classification.
• DEA number: NA.
• Narcotic: No.
• Street names: NA.

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CMH Mobile Integrated Healthcare Mission: "Provide exceptional, compassionate, and patient-centered care by a mobile collaborative team to improve patient experience, improve quality outcomes, and reduce healthcare costs."

Polk, Hickory, Cedar, & St Clair County EMS Protocols is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.