Medication 7-954 - Versed (Midazolam)

Polk, Hickory, Cedar, & St Clair EMS Protocols

Scope of Practice:

• Registered Nurse
• Paramedic

Route(s):

• IM/SQ, IN, IO, IV,

Pharmacodynamics (class and mechanism of action):

• Benzodiazepine (Sedative, anxiolytic, amnesic (2-3x more potent than Valium). Binds to benzodiazepine receptor and enhances effects of GABA).

Pharmacokinetics:

• Half-life: 1.8-6.4 hours.
• Onset time: 1.5-5 minutes.
• Peak action time: Rapid.
• Duration of action: 2-6 hours.

• Peak	24	48	72	96	120	144	168	192	216	240	264	minutes
  Duration	24	48	72	96	120	144	168	192	216	240	264	minutes

Dosing:

• Refer to specific protocol(s) below for dose(s).

Indications:

• Protocol 2-044 - Airway: RSI.
• Protocol 2-638 - Overdose / Toxic Ingestion.
• Protocol 2-660 - Pain Control.
• Protocol 2-792 - Seizure.
• Equipment 8-198 - Continuous Positive Airway Pressure.
• Equipment 8-288 - Endotracheal Tube.
• Equipment 8-486 - King Airway.
• Equipment 8-108 - Cardiac Monitor.

Contraindications:

• Pregnancy.
• Hypotension.
• Acute-angle glaucoma.

Pregnancy Risk Factor:

• Category D
• Positive evidence of risk: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Potential Incompatibilities:

• Medication 7-270 - Heparin.

Precautions and Adverse Effects:

• Use caution with COPD, acute alcohol intoxication, narcotics, barbiturates, elderly, and neonates.
• May cause hypoventilation, respiratory depression, respiratory arrest, hypotension, laryngospasm, Nausea, Vomiting, headache, hiccups, and/or Cardiac Arrest.

Antidote:

• Romazicon.

Controlled Substance Information:

• Schedule IV
• Moderate potential for abuse. Abusing the drug may lead to moderate mental or physical addiction.
• DEA number: 2884.
• Narcotic: No.
• Street names: Dazzle.

CMH PHS Mission: "Provide safe, exceptional, and compassionate care to our communities with an emphasis on highly trained and empowered staff."

Polk, Hickory, Cedar, & St Clair County EMS Protocols by Theron Becker is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.