Medication 7-801 - Reglan (Metoclopramide)

CMH EMS & MIH Protocols

Scope of Practice:

• Registered Nurse
• Paramedic
• Community Paramedic

Route(s):

• IO, IV,

Pharmacodynamics (class and mechanism of action):

• Gut motility stimulator. (Increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines. Also blocks dopamine receptors in the brain.)

Pharmacokinetics:

• Half-life: 4-6 hours.
• Onset time: 1-3 minutes.
• Peak action time: Unknown.
• Duration of action: 1-2 hours.

• Peak	9	18	27	36	45	54	63	72	81	90	99	minutes
  Duration	9	18	27	36	45	54	63	72	81	90	99	minutes

Dosing:

• Refer to specific protocol(s) below for dose(s).

Indications:

• Not in current standing order protocols.

Contraindications:

• Bleeding or blockage in stomach or intestines.
• Epilepsy or other Seizure disorder.
• Adrenal gland tumor (pheochromocytoma).

Pregnancy Risk Factor:

• Category B
• No risk in other studies: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women, or animal studies have shown adverse effects, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Potential Incompatibilities:

• None.

Precautions and Adverse Effects:

• High doses or long-term use can cause serious movement disorders that may not be reversible.
• Causes increased aldosterone and fluid retention.
• Use with caution with renal impairment, Hypertension, CHF, and cirrhosis.
• May cause neuroleptic malignant syndrome, Hyperthermia, muscle rigidity, and/or akathisia (fidgeting).
• Possible Extra-Pyramidal Symptoms (EPS) / dystonic reactions:
• EPS is a movement disorder such as the inability to move or restlessness.
• Treat with Medication 7-143 - Benadryl.

Antidote:

• None.

Controlled Substance Information:

• Not a scheduled drug
• The DEA and FDA have not identified this drug with a schedule classification.
• DEA number: NA.
• Narcotic: No.
• Street names: NA.

CMH Pre-Hospital Services Mission: "Provide safe, exceptional, and compassionate care to our communities with an emphasis on highly trained and empowered staff."

CMH Mobile Integrated Healthcare Mission: "Provide exceptional, compassionate, and patient-centered care by a mobile collaborative team to improve patient experience, improve quality outcomes, and reduce healthcare costs."

Polk, Hickory, Cedar, & St Clair County EMS Protocols is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.